[HTML][HTML] Antitumoral effects of tricyclic antidepressants: Beyond neuropathic pain treatment

A Asensi-Cantó, MD López-Abellán… - Cancers, 2022 - mdpi.com
… of antidepressants on the overall survival of the studied cohort of lung cancer patients [129]. …
TCAs translated to improved survival in patients with colorectal cancer or glioma showed no …

Antidepressants and colorectal cancer: A population-based nested case-control study

HC Lee, WC Chiu, TN Wang, YT Liao, IC Chien… - Journal of Affective …, 2017 - Elsevier
… Selective serotonin reuptake inhibitors (adjusted OR=1.00, 95% CI=0.94–1.06), tricyclic
antidepressants, serotonin-norepinephrine reuptake inhibitors, and serotonin antagonist and …

[HTML][HTML] Impact of polypharmacy for chronic ailments in colon cancer patients: a review focused on drug repurposing

R Giampieri, L Cantini, E Giglio, A Bittoni, A Lanese… - Cancers, 2020 - mdpi.com
… prevention of both colorectal cancer and glioma. The same group of authors in a following
paper [73] assessed the survival of CRC patients who used TCAs post-diagnosis: the authors …

[HTML][HTML] Depression and quality of life in patients with gliomas: a narrative review

Y Hu, F Deng, L Zhang, K Hu, S Liu, S Zhong… - Journal of Clinical …, 2022 - mdpi.com
… with shorter survival in patients with gliomas, and patients with gliomas with … antidepressant
use on the risk of glioma [85,86]. Tricyclic antidepressants (TCAs) reduce the risk of glioma

[PDF][PDF] Effect of treating depressive disorders on mortality of cancer patients

C Sherrill, M Smith, C Mascoe, E Bigus, D Abbitt - Cureus, 2017 - cureus.com
tricyclic antidepressant (TCA) use on the survival outcomes in patients with either glioma or
colorectal cancer… For colorectal patients, post-diagnosis TCA exposure was associated with a …

[PDF][PDF] Adherence to antidepressant medications is associated with reduced premature mortality in patients with cancer: A nationwide cohort study

I Aviv - kclpure.kcl.ac.uk
patients with either colorectal cancer or glioma, there was no significant mortality reduction
in those who used tricyclic antidepressants (… with increased survival in patients with cancer, …

Drug repurposing in cancer

L Sleire, HE Førde, IA Netland, L Leiss, BS Skeie… - Pharmacological …, 2017 - Elsevier
… for patients above 40 years with increased risk cardiovascular disease and colorectal cancer
… chemotherapy did not have any survival benefit compared to patients not on digoxin [79]. …

[HTML][HTML] Antidepressant use and colorectal cancer morbidity and mortality: a dose-response meta analysis

L Chen, X Li, C Li, C Zou - Medicine, 2020 - journals.lww.com
survival rate of colorectal liver metastases patients after surgical resection is up to 50%, but
only 20% of patients … inhibitor (SNRI) and tricyclic antidepressant (TCA) treat depression. The …

[HTML][HTML] Drug repositioning in glioblastoma: a pathway perspective

SK Tan, A Jermakowicz, AK Mookhtiar… - Frontiers in …, 2018 - frontiersin.org
treatment, which extends life in most cases. Unfortunately, tumor recurrence is nearly universal
and patients with recurrent glioblastoma typically survive <1 … approved for use in patients. …

[HTML][HTML] Pharmacological treatment of depression in people with a primary brain tumour

Z Beevers, S Hussain, FW Boele… - The Cochrane Database …, 2020 - ncbi.nlm.nih.gov
… of using tricyclic antidepressants for mortality reduction in people with glioma or colorectal
cancer. … , examining the relationship between depression and survival in glioma. However, the …